Bioinformatics Hub

Bioinformatics tools, workflows, and learning resources

A practical starter map for genomics and computational biology. Build reproducible analyses and share results with Runcell.

Runcell AI can make bioinformatics much easier by reducing the time spent coding and debugging so you can focus on the core idea. Check how to draw circos plot with runcell with simple text prompts.

Quick Tools

Sequence and lab utilities

Start with lightweight browser-side checks, then move into notebooks or longer workflows once the inputs are ready.

Reverse Complement
Flip DNA or RNA sequences, inspect complements, and copy the output instantly.
GC Content Calculator
Measure GC percentage, base counts, and sequence length for quick QC.
DNA Concentration Calculator
Convert ng/uL, nM, and pmol for dsDNA or ssDNA from sequence length.
Protein Concentration Calculator
Convert protein concentration and molarity from molecular weight.
Restriction Site Finder
Scan sequences for common restriction enzyme motifs in the browser.
Reproducibility
Make your work auditable and re-runnable.
Pin versions, record commands, and keep environment setup close to the analysis.
Pipelines First
Scale from laptop to cluster/cloud.
Use workflow managers (Nextflow/Snakemake/WDL) early—especially for NGS.
File Formats
Know your FASTQ, BAM/CRAM, VCF.
Many tools “click” once you understand common formats and indexing patterns (e.g., tabix).
Starter Kit

A curated bioinformatics toolkit map

The full ecosystem is huge. These sections highlight widely-used, open tools so you can get productive quickly (and build from there).

Package Suites
Language ecosystems and package channels that cover a large portion of day-to-day bioinformatics.
  • BioconductorR ecosystem for high-throughput genomic data (1500+ packages).Website
  • BiopythonPython tools for sequence/structure processing and NCBI Entrez access.Website
  • BiocondaConda channel specializing in bioinformatics tools (ready-to-install).Website
  • Rust-BioRust implementations of bioinformatics algorithms.
  • SeqAn3Modern C++ library for sequence analysis.
Workflow Managers
Reproducible pipelines, scalable execution (local/HPC/cloud), and provenance.
NGS Staples
A compact selection of tools used across QC, processing, alignment, and reporting.
Annotation & Visualization
Interpret variants, annotate genomes, and explore results interactively.
  • SnpEffVariant annotation and effect prediction.Website
  • Ensembl VEPAnnotate variants with gene/transcript/protein impacts and regulatory context.Website
  • ProkkaRapid prokaryotic genome annotation.
  • BaktaStandardized bacterial genome/plasmid annotation with rich dbxrefs.
  • IGVInteractive genome browser (desktop and web).Website
  • JBrowseCustomizable JavaScript genome browser.Website
  • CircosCircular plots for genomic rearrangements and links.Website
Next steps
Explore Runcell tools and start building a reproducible workflow you can share.
Resources

Learning and community

The fastest path is learning by doing—and staying connected to the community.

Learn Bioinformatics
High-signal places to build fundamentals and practice with real datasets.
Communities
Find peers, ask questions, and keep up with tooling and best practices.
Runcell

Run, share, and iterate on bioinformatics work faster

Keep analysis reproducible, collaborate in notebooks, and use Runcell’s developer tools to convert and publish results.

Fast iteration
Move between notebooks, scripts, and reports.
Privacy-first
Keep sensitive data in your environment.
Built for teams
Standardize workflows and share reproducible notebooks.